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Such subtle but widespread alterations of conduction velocity, which would perturb network synchronization in the brain, could be the substrate of frequent and disabling non-focal MS symptoms such as fatigue, mood disorders and cognitive decline (Kalb et al., 2019

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Clinical supervision matters: pharmaceutical-grade formulation and proper dosing separate an effective protocol from an expensive experiment

IL-21 is also a pleiotropic cytokine (525) important for differentiation of follicular helper T cells that are essential for the germinal centre antibody response (526)